skip to main content

Membranous Nephropathy Thrombosis — ESENeph MCQ

Instant feedback + full explanation. One question, done properly.

ModerateGlomerulonephritisMembranous Nephropathy ThrombosisESENeph

A 38-year-old woman presents with bilateral renal vein thrombosis, nephrotic syndrome, and anti-PLA2R-positive membranous nephropathy. Her albumin is 12 g/L. She is started on anticoagulation. According to KDIGO 2021, what level of hypoalbuminaemia triggers consideration for prophylactic anticoagulation in membranous nephropathy?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Serum albumin <20 g/L

KDIGO 2021 GN guideline specifically highlights membranous nephropathy as having the highest thrombotic risk among glomerular diseases. Prophylactic anticoagulation should be considered when serum albumin falls below 20 g/L (some guidelines suggest below 25 g/L based on individual bleeding risk). MN carries a particularly high risk of renal vein and deep vein thrombosis, with risk increasing as albumin falls.

Reference: KDIGO 2021 – Glomerular Disease Guideline