A 45-year-old woman is found to have hypercalcaemia (corrected Ca 2.92 mmol/L), AKI (creatinine 250 umol/L), and a uACR of 85 mg/mmol. She has a

Question

A 45-year-old woman is found to have hypercalcaemia (corrected Ca 2.92 mmol/L), AKI (creatinine 250 umol/L), and a uACR of 85 mg/mmol. She has a palpable left breast mass. Serum PTH is low. PTHrP is elevated. What is the cause of her kidney injury?

Accepted Answer

Malignancy-associated hypercalcaemia causing renal vasoconstriction, dehydration, and nephrocalcinosis

Answer

Sarcoidosis

Answer

Primary hyperparathyroidism

Answer

Vitamin D toxicity

Answer

Milk-alkali syndrome

Hypercalcaemia AKI Malignancy — ESENeph MCQ

A 45-year-old woman is found to have hypercalcaemia (corrected Ca 2.92 mmol/L), AKI (creatinine 250 umol/L), and a uACR of 85 mg/mmol. She has a palpable left breast mass. Serum PTH is low. PTHrP is elevated. What is the cause of her kidney injury?