Hookworm Egg Morphology — SCE Infectious Diseases MCQ
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Correct answer: E — Ancylostoma duodenale and Necator americanus — their eggs are morphologically identical; species identification requires larval culture (Harada-Mori or charcoal culture method)
Hookworm eggs (Ancylostoma duodenale and Necator americanus) are morphologically IDENTICAL on standard light microscopy — they cannot be distinguished by egg examination alone. Species identification requires: (1) larval culture (Harada-Mori filter paper technique or charcoal culture) to observe L3 larval morphology, or (2) molecular methods (PCR). This distinction matters clinically: A. duodenale is more pathogenic (higher blood loss per worm, can undergo oral transmission) while N. americanus is percutaneous only. Treatment is the same: Albendazole 400 mg single dose or Mebendazole 500 mg single dose.
Reference: WHO 2022 – Soil-transmitted helminths; UKHSA 2023