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EVS Trial Vitrectomy Threshold — SCE Infectious Diseases MCQ

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HardInfection Prevention & ControlEVS Trial Vitrectomy ThresholdSCE Infectious Diseases

After cataract surgery, culture-positive endophthalmitis presents with visual acuity 6/60. What did the Endophthalmitis Vitrectomy Study support regarding immediate vitrectomy?

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Correct answer: D — Clear benefit was confined to presentation with light-perception-only vision; 6/60 does not meet that trial threshold

The best answer is “Clear benefit was confined to presentation with light-perception-only vision; 6/60 does not meet that trial threshold”. The Endophthalmitis Vitrectomy Study found immediate vitrectomy benefit only for people presenting with light-perception-only vision. Visual acuity of 6/60 does not meet that threshold, so vitrectomy is not automatically indicated on this trial finding alone. Universal vitrectomy, a 14-day delay, and no vitrectomy role all misstate the evidence.

Reference: Endophthalmitis Vitrectomy Study: https://pubmed.ncbi.nlm.nih.gov/7487614/