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Post-SVR HCC Surveillance — SCE Infectious Diseases MCQ

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HardHepatitisPost-SVR HCC SurveillanceSCE Infectious Diseases

A person with HCV-related cirrhosis remains clinically compensated after SVR. Which surveillance test and interval remain appropriate?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BOffer liver ultrasound every 6 months for hepatocellular-carcinoma surveillance with review

The best answer is “Offer liver ultrasound every 6 months for hepatocellular-carcinoma surveillance with review”. Cirrhosis remains the determinant of surveillance even after virological cure; ultrasound at six-month intervals supports detection at a potentially curable stage. “Use alpha-fetoprotein alone without imaging” is less appropriate because it conflicts with the clinical discriminator or cited guidance. “Stop surveillance after 2 years of normal aminotransferases” is less appropriate because it conflicts with the clinical discriminator or cited guidance. “Restrict surveillance to decompensated disease” is less appropriate because it conflicts with the clinical discriminator or cited guidance. “Stop surveillance because SVR removes all HCC risk” is less appropriate because it conflicts with the clinical discriminator or cited guidance.

Reference: NICE NG50 cirrhosis recommendations: https://www.nice.org.uk/guidance/ng50/chapter/recommendations