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Limited KS Management — SCE Infectious Diseases MCQ

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ModerateHIV MedicineLimited KS ManagementSCE Infectious Diseases

A 30-year-old woman with HIV develops a painless violaceous gingival nodule. Biopsy shows HHV-8-positive spindle cells. She has well-controlled HIV (CD4 420, VL <50). The lesion is solitary and 1 cm. What is the initial management?

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Correct answer: EContinue ART and monitor — a solitary small KS lesion may regress with continued ART; local treatment for cosmetic reasons if desired

For limited T0-stage KS with well-controlled HIV, ART continuation and observation is reasonable. Local treatments (intralesional Vinblastine, radiation, cryotherapy) for cosmesis. Systemic chemo reserved for extensive/visceral KS.

Reference: BHIVA 2022 – HIV-associated malignancy; NICE 2023