Otogenic Brain Abscess — SCE Infectious Diseases MCQ
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Correct answer: E — IV Ceftriaxone 2 g BD plus IV Metronidazole 500 mg TDS
Otogenic brain abscess (temporal lobe or cerebellum) is caused by direct extension or haematogenous spread from chronic middle ear/mastoid infection. The microbiology reflects the middle ear flora: mixed aerobic-anaerobic organisms including streptococci (particularly S. anginosus group), anaerobes (Bacteroides, Prevotella, Fusobacterium), and Gram-negatives (Proteus, Pseudomonas). Empirical treatment is IV Ceftriaxone (covering streptococci and Gram-negatives) plus IV Metronidazole (anaerobes). Neurosurgical assessment for aspiration or excision is essential. Total duration is typically 6–8 weeks.
Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/infections