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Descending Necrotising Mediastinitis — SCE Infectious Diseases MCQ

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HardRespiratory InfectionDescending Necrotising MediastinitisSCE Infectious Diseases

A patient with an odontogenic deep-neck infection deteriorates despite antibiotics. CT shows gas-containing collections tracking below the carina into both pleural spaces. What is the definitive management priority?

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Correct answer: CCombined cervical and mediastinal drainage plus broad-spectrum intravenous antibiotics

This is descending necrotising mediastinitis with extension below the carina. Antibiotics alone are not curative: urgent airway and sepsis management, broad-spectrum therapy covering aerobic and anaerobic oral flora, and surgical drainage/debridement of the cervical and involved mediastinal or pleural spaces are required. The operative approach is determined by the extent on CT and specialist assessment.

Reference: Descending mediastinitis: a review: https://pmc.ncbi.nlm.nih.gov/articles/PMC11068289/; NHS UK-PAS antimicrobial guide: mediastinitis: https://www.royaldevon.nhs.uk/media/mcjdb4om/antimicrobial-paediatric-summary-ukpas.pdf