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Post-SVR HCC Risk — SCE Infectious Diseases MCQ

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HardHepatitisPost-SVR HCC RiskSCE Infectious Diseases

A 58-year-old with HCV-related compensated cirrhosis achieves sustained virological response after direct-acting antivirals. Liver stiffness falls and aminotransferases normalise. What surveillance remains appropriate?

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Correct answer: EContinue ultrasound with or without AFP every six months while treatment-eligible

Viral cure reduces but does not abolish hepatocellular-carcinoma risk in established cirrhosis. NICE recommends ultrasound surveillance, with or without AFP, every six months for adults with cirrhosis who are eligible for HCC treatment. Normal aminotransferases and lower stiffness after cure do not establish that the previous cirrhotic risk has disappeared.

Reference: NICE NG50: Cirrhosis in over 16s: https://www.nice.org.uk/guidance/ng50/chapter/recommendations