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Yellow Fever Vaccine Safety — SCE Infectious Diseases MCQ

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EasyTravel Medicine & VaccinationYellow Fever Vaccine SafetySCE Infectious Diseases

A 55-year-old woman presents to the travel clinic before a trip to Kenya. She has well-controlled asthma on Beclometasone inhaler only. She asks about Yellow Fever vaccination. Is the vaccine safe for her?

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Correct answer: B — Yes — inhaled corticosteroids are not a contraindication to live vaccines including Yellow Fever

Inhaled corticosteroids at standard doses are not systemically immunosuppressive and do not contraindicate live vaccines. Yellow Fever vaccine is safe for this patient. Contraindications to YF vaccine include: systemic immunosuppression (e.g. Prednisolone ≥20 mg/day for >2 weeks, chemotherapy, biological agents), primary immunodeficiency, HIV with CD4 <200, thymus disorders, age <6 months or ≥60 (caution), and severe egg allergy. The Green Book provides detailed eligibility criteria.

Reference: UKHSA 2024 – Green Book Ch 35: Yellow Fever; NaTHNaC 2024