MMR in HIV — SCE Infectious Diseases MCQ

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EasyTravel Medicine & VaccinationMMR in HIVSCE Infectious Diseases

A 32-year-old woman with well-controlled HIV (CD4 520, VL <50 on ART) is seen for routine vaccination assessment. She previously received 2 doses of MMR vaccine as a child (pre-HIV diagnosis). Does she need MMR revaccination?

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Correct answer: E — No revaccination needed — 2 documented doses of MMR provide adequate immunity even in well-controlled HIV

Patients with HIV who received 2 documented doses of MMR vaccine before HIV diagnosis (or while virally suppressed with CD4 >200) are considered adequately vaccinated. MMR is a live vaccine and can be given to PLWH with CD4 ≥200 cells/µL who lack immunity, but revaccination is not needed with documented prior vaccination history. If immunity is uncertain (no records), measles IgG should be checked and MMR offered if negative/equivocal and CD4 ≥200.

Reference: BHIVA 2024 – Vaccination in HIV; UKHSA 2024 – Green Book Ch 21: Measles