Intra-Abdominal Sepsis — SCE Infectious Diseases MCQ
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Correct answer: E — Drain the collection plus systemic anaerobic and enteric Gram-negative cover
The best answer is “Drain the collection plus systemic anaerobic and enteric Gram-negative cover”. Intra-abdominal infection requires source control plus an active regimen such as a suitable beta-lactam/beta-lactamase-inhibitor combination or metronidazole paired with Gram-negative cover. Sepsis care combines urgent risk-stratified antimicrobials with cultures where this does not delay treatment and documented review, narrowing or stopping when evidence changes.
Reference: NICE NG253: suspected sepsis in people aged 16 or over: https://www.nice.org.uk/guidance/ng253/chapter/Recommendations