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Dual STI Epididymo-orchitis — SCE Infectious Diseases MCQ

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EasySTIsDual STI Epididymo-orchitisSCE Infectious Diseases

A 35-year-old man develops acute epididymo-orchitis with positive NAAT for both Chlamydia trachomatis AND Neisseria gonorrhoeae from a urethral swab. He has no drug allergies. What treatment covers both organisms?

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Correct answer: B — Ceftriaxone 1 g IM single dose plus Doxycycline 100 mg BD for 14 days

Dual STI-associated epididymo-orchitis requires treatment covering both organisms: Ceftriaxone 1 g IM (for gonorrhoea — single dose) plus Doxycycline 100 mg BD for 14 days (for chlamydia plus epididymal tissue penetration). Doxycycline alone would not cover gonorrhoea. Ceftriaxone alone would not provide adequate duration for epididymal chlamydial infection. Azithromycin single dose is insufficient for epididymo-orchitis. Partner notification for both infections is essential.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/infections