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Endocarditis with Stroke — SCE Infectious Diseases MCQ

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HardBone & Joint InfectionEndocarditis with StrokeSCE Infectious Diseases

A 65-year-old man is diagnosed with infective endocarditis and develops acute embolic stroke. CT head confirms a large right MCA territory infarct without haemorrhagic transformation. His vegetation is 15 mm and mobile. He is haemodynamically stable. When should cardiac surgery for vegetation removal be considered?

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Correct answer: CEarly surgery (within days) is indicated for large vegetations (>10 mm) with embolic events, even after stroke — provided neurosurgical assessment confirms no contraindication

ESC 2023 endocarditis guidelines recommend early surgery (within days) for patients with large vegetations (>10 mm) plus embolic events, as the risk of further embolism is very high (~50% within 2 weeks). After embolic stroke, a multidisciplinary assessment (neurosurgery, neurology, cardiac surgery) should determine operative timing — surgery is generally safe if: the stroke is non-haemorrhagic, the infarct is not massive (affecting consciousness), and there is no haemorrhagic transformation. CT head should be repeated pre-operatively.

Reference: ESC 2023 – Endocarditis guidelines; AHA 2015 – IE and stroke