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Acute Prostatitis — SCE Infectious Diseases MCQ

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HardAntimicrobial StewardshipAcute ProstatitisSCE Infectious Diseases

A stable adult with acute bacterial prostatitis has fluoroquinolone-susceptible E. coli, eGFR 75 mL/min and no contraindication to ciprofloxacin. Which oral prescription and review point follow NICE NG110?

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Correct answer: A — Ciprofloxacin 500 mg twice daily for 14 days, then review and continue for a further 14 days if needed

The best answer is “Ciprofloxacin 500 mg twice daily for 14 days, then review and continue for a further 14 days if needed”. NICE recommends ciprofloxacin 500 mg twice daily for 14 days in susceptible acute bacterial prostatitis, then review and continue for a further 14 days if needed. Nitrofurantoin does not achieve therapeutic prostate levels; short courses of trimethoprim or co-amoxiclav are unsuitable. Culture results should refine therapy.

Reference: NICE NG110 acute prostatitis: https://www.nice.org.uk/guidance/ng110/chapter/Recommendations