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Chronic Norovirus — SCE Infectious Diseases MCQ

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HardImmunocompromised HostChronic NorovirusSCE Infectious Diseases

A solid-organ transplant recipient has three weeks of PCR-confirmed norovirus diarrhoea. Why is the illness often prolonged, and what management principle follows?

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Correct answer: ESupportive care plus cautious review of immunosuppression

The best answer is “Supportive care plus cautious review of immunosuppression”. Transplant immunosuppression can prevent viral clearance; fluid and electrolyte support is central, while specialist reduction of immunosuppression may be considered against rejection risk. Post-transplant infection management combines organism-directed supportive care with careful immunosuppression review because impaired cellular immunity can prolong viral shedding and disease.

Reference: Review of viral enteritis and systemic viral infection after transplantation: https://pmc.ncbi.nlm.nih.gov/articles/PMC7149989/