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Influenza — SCE Infectious Diseases MCQ

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HardRespiratory InfectionInfluenzaSCE Infectious Diseases

A renal-transplant recipient presents 72 hours after onset of PCR-confirmed influenza A with persistent fever, hypoxia and evolving pneumonia. Which antiviral approach follows UKHSA guidance?

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Correct answer: DOral oseltamivir with specialist duration and resistance review

Immunosuppression and severe ongoing lower-respiratory disease justify prompt antiviral treatment even after the optimal 48-hour window. UKHSA uses oseltamivir first-line and advises specialist input about prolonged treatment and resistance in severe or immunosuppressed patients. Inhaled zanamivir may be inappropriate in severe respiratory disease.

Reference: UKHSA influenza antiviral guidance: https://www.gov.uk/government/publications/influenza-treatment-and-prophylaxis-using-anti-viral-agents/guidance-on-use-of-antiviral-agents-for-the-treatment-and-prophylaxis-of-seasonal-influenza