HPV Vaccination — SCE Infectious Diseases MCQ
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Correct answer: E — Offer HPV vaccination under the age- and risk-appropriate UK schedule; prior sexual activity and HIV do not make the vaccine contraindicated after review with follow-up clinically-reassessed
The best answer is “Offer HPV vaccination under the age- and risk-appropriate UK schedule; prior sexual activity and HIV do not make the vaccine contraindicated after review with follow-up clinically-reassessed”. Vaccination cannot treat established infection but can protect against types not yet acquired, and immunocompromised schedules use additional doses where specified. “Withhold vaccine because it works only before any sexual contact” does not match the decisive clinical feature or cited guidance. “Withhold vaccine because HIV is a contraindication” does not match the decisive clinical feature or cited guidance. “Use only a bivalent product because nonavalent vaccine is unsafe” does not match the decisive clinical feature or cited guidance. “Vaccinate only if CD4 exceeds 500 cells/µL” does not match the decisive clinical feature or cited guidance.
Reference: UKHSA Green Book chapter 18a: HPV: https://www.gov.uk/government/publications/human-papillomavirus-hpv-the-green-book-chapter-18a