Epididymo-orchitis — SCE Infectious Diseases MCQ
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Correct answer: A — Doxycycline 100 mg BD for 10–14 days
In sexually acquired epididymo-orchitis with confirmed Chlamydia and negative gonococcal NAAT, Doxycycline 100 mg BD for 10–14 days is the appropriate treatment. If gonorrhoea were also suspected or confirmed, IM Ceftriaxone would be added. In men >35 or those unlikely to have an STI aetiology, Ofloxacin covering enteric organisms is appropriate. Azithromycin single dose is insufficient for epididymo-orchitis.
Reference: BASHH 2020 – Epididymo-orchitis guidelines; NICE CKS 2024 – Epididymo-orchitis