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Pelvic Inflammatory Disease — SCE Infectious Diseases MCQ

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ModerateSTIsPelvic Inflammatory DiseaseSCE Infectious Diseases

A 25-year-old woman presents with a week-long history of vaginal discharge and lower abdominal pain. She is febrile (38.2°C). Pelvic examination reveals cervical excitation tenderness. NAAT is positive for Chlamydia trachomatis. Pregnancy test is negative. What is the most appropriate treatment?

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Correct answer: EIM Ceftriaxone 1 g single dose plus oral Doxycycline 100 mg BD for 14 days plus oral Metronidazole 400 mg BD for 14 days

This presentation is consistent with pelvic inflammatory disease (PID). BASHH guidelines recommend empirical treatment covering N. gonorrhoeae, C. trachomatis, and anaerobes: IM Ceftriaxone 1 g (single dose) plus oral Doxycycline 100 mg BD for 14 days plus oral Metronidazole 400 mg BD for 14 days. Azithromycin single dose is insufficient for PID. Moxifloxacin is an alternative in mild-moderate PID but is not first-line.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/infections