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Metformin Safety in HF — EECC MCQ

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HardHeart FailureMetformin Safety in HFEECC

A patient with hypereosinophilic syndrome develops restrictive physiology. CMR shows apical obliteration, layered LV thrombus and diffuse subendocardial enhancement of the apices. What cardiac manifestation is present?

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Correct answer: D — Loeffler endocarditis

Eosinophilic endomyocardial injury evolves from necrosis through thrombosis to fibrosis, producing apical thrombus, obliteration and restrictive haemodynamics. This is Loeffler endocarditis, a cardiac manifestation of hypereosinophilic disease requiring treatment of inflammation and thrombosis.

Reference: https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines