Heart Failure Diagnosis — EECC MCQ
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Correct answer: B — Less than 300 pg/mL
Explanation lettering: C = shown as A · D = shown as B · A = shown as C · B = shown as D
Per the 2021 ESC HF Guidelines, NT-proBNP below 300 pg/mL has a high negative predictive value and is used to rule out acute heart failure. For non-acute presentations, the threshold is lower at below 125 pg/mL (C). Option A (100 pg/mL) is the BNP threshold, not NT-proBNP. Options D and E are not standard thresholds.
Reference: ESC (2021): Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure