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GDMT Withdrawal TRED-HF — EECC MCQ

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HardHeart FailureGDMT Withdrawal TRED-HFEECC

A 22-year-old athlete has anomalous origin of the left coronary artery from the right sinus with an intramural interarterial course. Stress perfusion CMR produces anterior ischaemia and exertional presyncope. What management is preferred?

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Correct answer: CRefer for surgical correction at an experienced congenital coronary centre

A left coronary artery arising from the opposite sinus with a high-risk intramural/interarterial course, symptoms and demonstrable ischaemia warrants surgical evaluation. Normal resting function does not remove exertional risk; aspirin, septal ablation and an ICD do not correct ostial compression or the intramural segment.

Reference: 2020 ESC Guidelines for adult congenital heart disease. https://academic.oup.com/eurheartj/article/42/6/563/5898606