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DOAC Acceptable with Bioprosthetic Valve — EECC MCQ

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HardValvular Heart DiseaseDOAC Acceptable with Bioprosthetic ValveEECC

A patient has exertional breathlessness, LVEF 62%, normal resting filling pressures and an intermediate HFA-PEFF score. During supine cycle right-heart catheterisation, pulmonary-capillary wedge pressure rises from 11 to 27 mmHg at 50 W. What does this establish?

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Correct answer: AHeart failure with preserved ejection fraction unmasked by exercise haemodynamics

When resting data are equivocal, exercise haemodynamics can reveal HFpEF. A wedge pressure of at least 25 mmHg during supine exercise indicates pathological elevation of left-sided filling pressure. Pre-capillary pulmonary hypertension is defined by pulmonary vascular haemodynamics, while the other diagnoses do not account for the measured wedge-pressure response.

Reference: 2021 ESC Guidelines for acute and chronic heart failure. https://academic.oup.com/eurheartj/article/42/36/3599/6358045