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Peripartum Cardiomyopathy — EECC MCQ

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HardHeart FailurePeripartum CardiomyopathyEECC

A woman with a mechanical mitral valve is booked for induction at 38 weeks. She is receiving therapeutic twice-daily low-molecular-weight heparin with anti-Xa monitoring and has no labour symptoms. Which peripartum anticoagulation plan is most appropriate?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AConvert to intravenous unfractionated heparin in hospital before the planned delivery

Mechanical mitral valves carry high thrombosis risk, yet therapeutic LMWH close to delivery complicates neuraxial anaesthesia and haemostasis. Planned hospital delivery permits conversion to short-acting IV unfractionated heparin, which can be stopped 4–6 hours before delivery and restarted postpartum when haemostasis permits. Uninterrupted LMWH, an unbridged prolonged gap, warfarin at delivery and aspirin monotherapy are unsafe alternatives.

Reference: 2025 ESC Guidelines for cardiovascular disease and pregnancy. https://academic.oup.com/eurheartj/article/46/43/4462/8234487