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Amiodarone Monitoring — EECC MCQ

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ModerateCardiac PharmacologyAmiodarone MonitoringEECC

A 70-year-old man with persistent atrial fibrillation is started on amiodarone for rhythm control. He has a history of treated hypothyroidism (currently euthyroid on levothyroxine). What monitoring is essential before and during amiodarone therapy?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BThyroid function tests and liver function tests at baseline, then every 6 months

Explanation lettering: C = shown as B · E = shown as C · B = shown as E

Amiodarone has well-known thyroid, hepatic, pulmonary, and ophthalmic toxicities. Per BNF, TFTs and LFTs should be performed at baseline and then every 6 months during therapy. Amiodarone can cause both hypo- and hyperthyroidism. Serum amiodarone levels (D) are not routinely measured. Annual echo alone (B) is insufficient. Stopping monitoring (E) is dangerous given pre-existing thyroid disease.

Reference: BNF: Amiodarone Hydrochloride