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Lenient vs Strict Rate Control — EECC MCQ

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EasyArrhythmia & ElectrophysiologyLenient vs Strict Rate ControlEECC

A 68-year-old man with permanent AF on bisoprolol 5 mg for rate control has a resting ventricular rate of 95 bpm. He is asymptomatic and has LVEF 50%. What is the recommended heart rate target for rate control in AF?

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Correct answer: AA lenient rate control target of resting heart rate <110 bpm is acceptable in asymptomatic patients with preserved LVEF, based on the RACE II trial

The RACE II trial demonstrated that lenient rate control (resting HR <110 bpm) was non-inferior to strict rate control (resting HR <80 bpm) for a composite of CV death, HF hospitalisation, stroke, systemic embolism, bleeding, and life-threatening arrhythmias in permanent AF with preserved LV function. The 2024 ESC AF Guidelines recommend: lenient rate control (<110 bpm at rest) as an acceptable initial target for most patients (Class IIa). Stricter rate control may be needed for patients with: ongoing symptoms despite lenient control, HFrEF, or tachycardia-mediated cardiomyopathy. This patient at 95 bpm with preserved LVEF and no symptoms has adequate rate control.

Reference: ESC (2024): Guidelines for the Management of Atrial Fibrillation; RACE II Trial