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SVC Stent Re-Occlusion — SCE Palliative Medicine MCQ

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HardRespiratory SymptomsSVC Stent Re-OcclusionSCE Palliative Medicine

Two weeks after initially successful stenting for malignant superior vena cava obstruction, a patient again develops facial swelling and venous distension. Imaging shows loss of flow through the stent. Which mechanism most plausibly explains recurrence?

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Correct answer: AIn-stent thrombosis or tumour ingrowth causing recurrent luminal obstruction

Recurrent malignant SVCO after an initially effective stent should prompt imaging and interventional reassessment. Recognised mechanisms include in-stent thrombosis, tumour ingrowth or overgrowth, and less commonly migration. Anticoagulation is not automatically indicated without defining thrombosis and bleeding risk, so management was removed from the keyed diagnosis.

Reference: NICE HTG50: Stent placement for vena caval obstruction. https://www.nice.org.uk/guidance/htg50/resources/stent-placement-for-vena-caval-obstruction-pdf-50266559988421 BMJ review: Endovascular stenting for superior vena cava obstruction. https://pmc.ncbi.nlm.nih.gov/articles/PMC2432169/