A 38-year-old man presents with dyspepsia. He is taking naproxen 500 mg BD. Endoscopy shows multiple superficial gastric erosions without ulceration. ...

Question

A 38-year-old man presents with dyspepsia. He is taking naproxen 500 mg BD. Endoscopy shows multiple superficial gastric erosions without ulceration. CLO test is negative. He cannot stop NSAIDs. What is the most appropriate gastroprotective strategy?

Accepted Answer

Co-prescribe a PPI (e.g. omeprazole 20 mg OD)

Answer

Switch to a COX-2 selective inhibitor alone

Answer

Add sucralfate

Answer

Co-prescribe misoprostol 200 µg QDS

Answer

Switch to paracetamol only

uk-sce-gastroenterology MCQ (SBA): NSAID Gastropathy

A 38-year-old man presents with dyspepsia. He is taking naproxen 500 mg BD. Endoscopy shows multiple superficial gastric erosions without ulceration. CLO test is negative. He cannot stop NSAIDs. What is the most appropriate gastroprotective strategy?