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Post-Endoscopic PPI — ESEGH MCQ

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Hard"Gastroenterology"Post-Endoscopic PPIESEGH

A 58‑year‑old patient with peptic ulcer bleeding undergoes successful endoscopic hemostasis. Which proton pump inhibitor strategy is recommended by current UK gastroenterology guidance?

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Correct answer: A — High-dose continuous or intermittent PPI therapy for 72 hours

The best answer is “High-dose continuous or intermittent PPI therapy for 72 hours”. High‑dose intravenous bolus with continuous infusion for 72 hours, or, alternatively, intermittent high‑dose intravenous or oral dosing The alternatives “Standard once‑daily oral PPI dosing, when clinically appropriate”, “No PPI therapy after endoscopic hemostasis, after specialist review”, “Intravenous H₂‑receptor antagonist infusion, within a guideline-based pathway”, “High‑dose intravenous PPI for 24 hours then stop” are plausible in related gastroenterology presentations but do not match the defining finding, threshold, sequence or UK pathway in this stem.

Reference: NICE CG141 acute upper gastrointestinal bleeding: https://www.nice.org.uk/guidance/cg141/chapter/Recommendations