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Acute Ischaemic Stroke — SCE Neurology MCQ

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EasyEarly Management of Acute Ischaemic StrokeAcute Ischaemic StrokeSCE Neurology

A patient with acute ischaemic stroke is eligible for IV alteplase. What is the recommended dose and administration?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E0.75 mg/kg IV bolus only

The UK stroke guidance recommends 0.9 mg/kg (max 90 mg) with 10% given as a 1-minute bolus and the remainder over 60 minutes. Other dosing regimens are incorrect for standard alteplase in stroke.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/neurological-conditions