Gastrointestinal Bleed — SCE Acute Medicine MCQ

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EasySpontaneous ICHGastrointestinal BleedSCE Acute Medicine

A 63-year-old with GI bleed on rivaroxaban stabilized post-endoscopy asks about reversal agents in future emergencies. Which reverses rivaroxaban?

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Reveal the answer and explanation

Correct answer: D — Andexanet alfa

Andexanet alfa reverses factor Xa inhibitors; idarucizumab reverses dabigatran. Vitamin K reverses VKA. Protamine reverses heparin. TXA is antifibrinolytic, not a reversal agent.

Reference: AHA/ASA Guideline (2022): Spontaneous ICH (Reversal Agents)