Streptococcal Pharyngitis (allergy) — Medical Practice MCQ

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ModerateInfectious DiseasesStreptococcal Pharyngitis (allergy)

A 49-year-old with severe sore throat and penicillin anaphylaxis has positive rapid strep test. Best therapy?

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Correct answer: E — Azithromycin (consider resistance)

For GAS pharyngitis with true penicillin allergy, macrolide can be used (consider local resistance). Cephalosporins risk cross-reactivity in anaphylaxis. Amoxicillin inappropriate with allergy. Levofloxacin not first-line. No antibiotics incorrect with positive test.

Reference: IDSA (2012): GAS Pharyngitis Guideline (Secondary Source)