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AF (AKI and DOAC Management) — EECC MCQ

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HardCardiologyAF (AKI and DOAC Management)EECC

A 70-year-old with AF and prior stroke on apixaban presents with GI illness causing dehydration. Creatinine rises from 88-186 µmol/L (eGFR now 28). What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AAssess renal function and consider temporary dose adjustment or hold if acute kidney injury is severe, then resume per labeling

Renal function changes warrant reassessment for DOAC dosing/temporary holds in acute kidney injury, then resumption per approved dosing once stable. Permanent cessation or adding aspirin is inappropriate.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cardiovascular-conditions