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CKD Evaluation — ESENeph MCQ

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ModerateNephrologyCKD EvaluationESENeph

A 70-year-old with CKD G3bA3 (eGFR 38; UACR 420 mg/g) and hypertension is on an ARB. According to CKD guidelines, which additional test best refines GFR estimation for drug dosing and risk?

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Correct answer: A — Serum cystatin C to calculate creatinine-cystatin C eGFR

KDIGO 2024 recommends using cystatin C (alone or combined with creatinine) to improve GFR estimation in selected patients (e.g., extremes of muscle mass, drug dosing decisions). Timed urine collections are less practical; creatinine alone may be inaccurate.

Reference: KDIGO Guideline (2024): Evaluation and Management of Chronic Kidney Disease