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Diabetic Kidney Disease — ESENeph MCQ

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EasyNephrologyDiabetic Kidney DiseaseESENeph

A 51-year-old with type 2 diabetes and CKD (eGFR 32 mL/min/1.73 m²; UACR 420 mg/g) is on metformin and ACE inhibitor. Which additional therapy has kidney and cardiovascular benefit and should be started?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CEmpagliflozin

KDIGO recommends SGLT2 inhibitors for T2D with CKD and eGFR ≥20 mL/min/1.73 m² with albuminuria to reduce CKD progression and CV events. Other agents listed do not provide comparable renal/CV protection.

Reference: KDIGO Guideline (2022): Diabetes Management in Chronic Kidney Disease