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AF with PCI — EECC MCQ

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HardCardiologyAF with PCIEECC

A 70-year-old with NSTEMI and atrial fibrillation (on apixaban) undergoes PCI with a drug-eluting stent. After initial peri-procedural management, what long-term plan minimises bleeding while protecting stent?

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Correct answer: A — Short course of triple therapy then dual therapy (OAC + P2Y12), then OAC alone by 6-12 months

Guidelines support a very short course of triple therapy (days to a month) followed by OAC + P2Y12 inhibitor, then OAC monotherapy by 6-12 months, balancing ischaemia and bleeding risks. Prolonged triple therapy increases bleeding.

Reference: ACC/AHA/ACCP/HRS Guideline (2023): Atrial Fibrillation