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Influenza — Medical Practice MCQ

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ModerateInfectious DiseasesInfluenza

A 67-year-old with COPD and heart failure develops influenza-like illness for 36 hours during flu season. Renal function normal. Recommended antiviral therapy?

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Correct answer: A — Oseltamivir 75 mg orally twice daily for 5 days

High-risk patients (e.g., COPD, HF) benefit from antiviral treatment even beyond 48 hours; standard oseltamivir dosing is 75 mg BID for 5 days. Peramivir is single-dose IV for uncomplicated cases; oseltamivir once-daily is prophylaxis. Baloxavir is single dose, not for 5 days.

Reference: CDC Guidance (2023-2025): Influenza Antiviral Medications-Summary for Clinicians