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NASH Therapy — ESEGH MCQ

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HardGastroenterologyNASH TherapyESEGH

An adult with biopsy-proven F3 steatohepatitis and diabetes is reviewed in hepatology. Which pharmacological statement matches NICE NG49?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Specialist pioglitazone or vitamin E after comorbidity review

Explanation lettering: C = shown as A · E = shown as B · B = shown as C · A = shown as E

C is correct. NICE limits consideration of pioglitazone or vitamin E to adults with advanced fibrosis in secondary/tertiary care, whether diabetic or not, after risk assessment. A invents a diabetes exclusion; B ignores contraindications; D lacks fibrosis-specific benefit; E delays beyond the eligible F3 stage.

Reference: NICE NG49 NAFLD recommendations: https://www.nice.org.uk/guidance/ng49/chapter/Recommendations