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Diabetic Kidney Disease (RAS blockade) — ESENeph MCQ

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EasyNephrologyDiabetic Kidney Disease (RAS blockade)ESENeph

A 64-year-old with diabetes and microalbuminuria (UACR 80 mg/g) has BP 136/84. Best first-line antihypertensive approach?

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Correct answer: E — Start ACE inhibitor or ARB

ACEi/ARB are preferred first-line in diabetes with albuminuria to slow kidney disease. β-blockers are not first-line without compelling indications. Dual RAS blockade increases harm. Loop diuretics are not initial therapy for BP control here.

Reference: ADA Standards of Care (2025): Standards of Care in Diabetes