A 62-year-old with HFrEF reports nocturnal cough after starting sacubitril/valsartan. K 4.5, creatinine stable. What is the most likely cause and acti...

Question

A 62-year-old with HFrEF reports nocturnal cough after starting sacubitril/valsartan. K 4.5, creatinine stable. What is the most likely cause and action?

Accepted Answer

Bradykinin effect is less with ARNI; continue and evaluate other causes

Answer

ACE-inhibitor cough from ARNI; stop immediately

Answer

Hyperkalemia causing cough

Answer

Acute kidney injury causing cough

Answer

Allergy requiring epinephrine

us-abim MCQ (SBA): HFrEF-Adverse Effect Assessment

A 62-year-old with HFrEF reports nocturnal cough after starting sacubitril/valsartan. K 4.5, creatinine stable. What is the most likely cause and action?