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CAP With Pseudomonas Risk — Medical Practice MCQ

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HardInfectious DiseasesCAP With Pseudomonas Risk

A 67-year-old with CAP and risk factors for Pseudomonas (structural lung disease and recent IV antibiotics) requires empiric therapy. Which is appropriate?

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Correct answer: A — Piperacillin-tazobactam plus azithromycin

In patients with validated Pseudomonas risk factors, include antipseudomonal β‑lactam plus atypical coverage. Ceftriaxone lacks Pseudomonas coverage; monotherapy may be inadequate; amoxicillin/clavulanate is insufficient.

Reference: IDSA/ATS Guideline (2019): Community-Acquired Pneumonia in Adults