AF with CKD — EECC MCQ

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HardCardiologyAF with CKDEECC

A 64-year-old with AF and stage 4 CKD (eGFR 24) needs anticoagulation. Which is most appropriate?

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Correct answer: C — Apixaban with dose adjustment per labeling

Apixaban has labeling for use in severe CKD with dose adjustments; dabigatran/rivaroxaban dosing is limited in advanced CKD; aspirin alone is inadequate; anticoagulation is not absolutely contraindicated by CKD alone.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cardiovascular-conditions