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Community-Acquired Pneumonia — Medical Practice MCQ

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ModerateInfectious DiseasesCommunity-Acquired Pneumonia

A 73-year-old with suspected CAP and risk factors for MRSA (recent influenza with necrotizing pneumonia in community) is hospitalized. What empiric regimen is appropriate?

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Correct answer: C — Ceftriaxone plus azithromycin plus vancomycin

For CAP with MRSA risk, add anti-MRSA coverage (e.g., vancomycin) to standard regimen. Ceftriaxone/azithro alone or FQ monotherapy may miss MRSA; cefepime alone misses atypicals; amoxicillin/clavulanate is insufficient for inpatient CAP.

Reference: IDSA/ATS Guideline (2019): Community-Acquired Pneumonia in Adults