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Variceal Bleeding — ESEGH MCQ

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HardGastroenterologyVariceal BleedingESEGH

A patient with genetically confirmed HFE haemochromatosis begins standard therapeutic phlebotomy. Haemoglobin remains adequate and treatment is tolerated. Which ferritin targets align with EASL guidance?

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Correct answer: D — Below 50 micrograms/L during induction, then 50–100 micrograms/L during maintenance

D is correct. EASL targets ferritin below 50 micrograms/L during iron-depletion induction and 50–100 micrograms/L during maintenance. A risks unnecessary iron deficiency. B leaves excessive stores during maintenance. C incorrectly substitutes transferrin saturation for ferritin monitoring. E accepts concentrations above therapeutic targets in both phases.

Reference: EASL haemochromatosis clinical practice guideline: https://easl.eu/wp-content/uploads/2022/06/PIIS01688278220021121.pdf