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Asymptomatic Bacteriuria (Pregnancy) — UKMLA MCQ

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EasyInfectious DiseasesAsymptomatic Bacteriuria (Pregnancy)UKMLA

A 36-year-old pregnant patient (12 weeks) with asymptomatic bacteriuria shows E. coli 10^5 CFU/mL. Appropriate management?

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Correct answer: CNitrofurantoin for 5-7 days

Asymptomatic bacteriuria in pregnancy should be treated; nitrofurantoin for 5-7 days is appropriate (avoid near term). Untreated asymptomatic bacteriuria increases the risk of pyelonephritis. TMP-SMX should be avoided in the first trimester if alternatives exist. Fluoroquinolones should be avoided. Single-dose fosfomycin is an acceptable alternative and is not contraindicated.

Reference: IDSA Guideline (2019): Asymptomatic Bacteriuria