AF Anticoagulant Safety — EECC MCQ

Instant feedback + full explanation. One question, done properly.

HardCardiologyAF Anticoagulant SafetyEECC

A 64-year-old with a history of GI bleeding and atrial fibrillation needs anticoagulation. Which direct oral anticoagulant (DOAC) has a comparatively lower risk of GI bleeding and is reasonable to choose?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Apixaban 5 mg twice daily

Apixaban has demonstrated a lower risk of gastrointestinal (GI) bleeding compared to other direct oral anticoagulants (DOACs) while maintaining comparable efficacy for stroke prevention in atrial fibrillation. Aspirin alone is insufficient for stroke prevention in atrial fibrillation, and other DOACs have shown higher GI bleeding rates in comparative studies.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cardiovascular-conditions