A 17-year-old boy has recurrent Serratia and Aspergillus infections, granulomatous obstruction and lymph-node infection with catalase-positive organis...

Question

A 17-year-old boy has recurrent Serratia and Aspergillus infections, granulomatous obstruction and lymph-node infection with catalase-positive organisms. Immunoglobulins and lymphocyte subsets are normal. Which test most directly confirms chronic granulomatous disease?

Accepted Answer

Dihydrorhodamine flow cytometry of neutrophil oxidative burst

Answer

CH50 measurement of the classical complement pathway

Answer

Serum IgG subclass quantification

Answer

T-cell receptor excision-circle testing

Answer

Direct antiglobulin testing of red cells

Atrial Fibrillation — MRCP Part 1 MCQ

A 17-year-old boy has recurrent Serratia and Aspergillus infections, granulomatous obstruction and lymph-node infection with catalase-positive organisms. Immunoglobulins and lymphocyte subsets are normal. Which test most directly confirms chronic granulomatous disease?