Tdap in Pregnancy — USMLE Step 2 CK MCQ

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EasyObstetrics & GynecologyTdap in PregnancyUSMLE Step 2 CK

A 28-year-old at 30 weeks' gestation has not received Tdap this pregnancy. What is recommended?

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Correct answer: C — Tdap at 27-36 weeks' gestation in each pregnancy

ACIP recommends Tdap during each pregnancy, optimally at 27-36 weeks, to maximize passive antibody transfer. Postpartum only (A) misses neonatal protection. First trimester only (B) is not optimal. Td alone (D) is inadequate. Stating no vaccination (E) is incorrect.

Reference: CDC/ACIP (2025): Recommended Adult Immunization Schedule, United States