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Recurrent peptic ulcer bleeding — UKMLA MCQ

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MediumGastroenterologyRecurrent peptic ulcer bleedingUKMLAMRCP Part 1

A 60-year-old with recurrent peptic ulcer bleeding on aspirin for CAD asks about PPI co-therapy. What is recommended?

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Correct answer: A — Continue aspirin for secondary prevention and use daily PPI co-therapy

Continue aspirin with PPI co-therapy to reduce rebleeding. Stopping aspirin permanently increases cardiovascular risk. H2 blockers are less effective for high-risk ulcers. Alternate-day aspirin is not guideline-based. Clopidogrel without PPI does not necessarily reduce gastrointestinal risk.

Reference: ACG Guideline (2021): Upper Gastrointestinal and Ulcer Bleeding